| Field | Specification |
|---|---|
| Target | |
| Alternative names | METTL11B; C1orf184; NRMT2; Alpha N-terminal protein methyltransferase 1B; EC 2.1.1.299; Methyltransferase-like protein 11B; X-Pro-Lys N-terminal protein methyltransferase 1B; NTM1B |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived human NTMT2 recombinant protein (Position: M1-S283). Human NTMT2 shares 93.6% and 93.3% amino acid (aa) sequence identity with mouse and rat NTMT2, respectively. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody recognizes N-terminal Xaa-Pro-Lys N-methyltransferase 2 (gene NTMT2) in human and rat samples and is validated for Western blot and ELISA.
NTMT2 (METTL11B) is an N-terminal methyltransferase closely related to NTMT1 that methylates proteins starting with an X-Pro-Lys motif. It works mainly as a monomethylase and can prime substrates for further methylation by NTMT1, making it of interest in studies of protein N-terminal modification.
| Target | N-terminal Xaa-Pro-Lys N-methyltransferase 2 (gene NTMT2; UniProt Q5VVY1, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Human, Rat |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.25–0.5 µg/mL (Rat) |
|---|---|
| ELISA | 0.1–0.5 µg/mL (Human) |
Immunogen
Recombinant human NTMT2 fragment (Met1–Ser283), expressed in E. coli. Sequence identity with the mouse and rat orthologs: 93.6% and 93.3%, respectively.
Reactivity Notes
The supplier lists reactivity with human and rat. UniProt places N-terminal Xaa-Pro-Lys N-methyltransferase 2 in the nucleus.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
