| Field | Specification |
|---|---|
| Target | |
| Alternative names | MHC class II associated invariant chain; MHC; Ii |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Conjugate | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody detects MHC class II associated invariant chain (gene MHC Ii) in Nurse shark samples.
In the nurse shark (Ginglymostoma cirratum), this protein is the MHC class II-associated invariant chain, the counterpart of mammalian CD74. In vertebrates, the invariant chain acts as a chaperone that helps assemble MHC class II molecules and directs them to endosomal compartments for antigen loading, and cartilaginous fish are studied as early vertebrates with MHC-based adaptive immunity.
| Target | MHC class II associated invariant chain (gene MHC Ii; UniProt H2BJQ3, Ginglymostoma cirratum) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Nurse shark |
| Form | Liquid |
| Formulation | 20 mM PBS; 50% glycerol; 0.02% NaN3 |
| Storage | Store at −20 °C for up to 12 months or 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Reactivity Notes
The supplier lists reactivity with Nurse shark. UniProt describes MHC class II associated invariant chain as a secreted protein.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
