| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | PABPN1; PAB2; PABP2; Polyadenylate-binding protein 2; PABP-2; Poly(A-binding protein 2; Nuclear poly(A-binding protein 1; Poly(A-binding protein II; PABII; Polyadenylate-binding nuclear protein 1 |
| Clonality | |
| Concentration | |
| Gene ID | |
| Host | |
| Immunogen | A synthetic peptide corresponding to a sequence in the middle region of human PABPN1. Human PABPN1 shares 100% amino acid (aa) sequence identity with mouse PABPN1. |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-PABPN1 Antibody Picoband® catalog # A02445-2. Tested in WB, IHC, IF, ICC, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Scientific background: This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.
Cross reactivity: No cross-reactivity with other proteins
Protein: Polyadenylate-binding protein 2 | Gene: poly(A) binding protein nuclear 1 | Target: PABPN1
Host: Rabbit | Clonality/Clone: Polyclonal | Isotype: Rabbit IgG | Reactivity: Human,Mouse,Rat | Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human PABPN1. Human PABPN1 shares 100% amino acid (aa) sequence identity with mouse PABPN1. | Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. | Purification: Immunogen affinity purified.
Applications: WB, IHC, IF, ICC, FC, IP, ELISA
Observed MW: 50 kDa | Calculated MW: 33 kDa
Status: Active
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.