| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | PADI2; KIAA0994; PAD2; PDI2; Protein-arginine deiminase type-2; EC 3.5.3.15; PAD-H19; Peptidylarginine deiminase II; Protein-arginine deiminase type II |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | E.coli-derived human PADI2 recombinant protein (Position: Q38-K640). Human PADI2 shares 92.7% and 93.2% amino acid (aa) sequence identity with mouse and rat PADI2, respectively. |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-PADI2 Antibody Picoband® catalog # A06877. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Scientific background: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.
Cross reactivity: No cross-reactivity with other proteins
Protein: Protein-arginine deiminase type-2 | Gene: peptidyl arginine deiminase 2 | Target: PADI2
Host: Rabbit | Clonality/Clone: Polyclonal | Isotype: Rabbit IgG | Reactivity: Human,Mouse,Rat | Immunogen: E.coli-derived human PADI2 recombinant protein (Position: Q38-K640). Human PADI2 shares 92.7% and 93.2% amino acid (aa) sequence identity with mouse and rat PADI2, respectively. | Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. | Purification: Immunogen affinity purified.
Applications: WB, IHC, ICC, FC, ELISA
Observed MW: 75 kDa | Calculated MW: 75 kDa
Status: Active
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