| Field | Specification |
|---|---|
| Target | |
| Alternative names | Pannexin-3; PANX3 |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived human PANX3 recombinant protein (Position: M1-P392). Human PANX3 shares 89% and 91.6% amino acid (aa) sequence identity with mouse and rat PANX3, respectively. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody targets pannexin-3 (gene PANX3) in human samples and is validated for Western blot, flow cytometry and ELISA.
Pannexin-3 (PANX3) is a pannexin channel protein expressed in skin, cartilage and bone. It can release ATP and act as an endoplasmic reticulum Ca2+ channel, and is studied for its role in osteoblast and chondrocyte differentiation.
| Target | Pannexin-3 (gene PANX3; UniProt Q96QZ0, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / IgG |
| Reactivity | Human |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.25–0.5 µg/mL (Human) |
|---|---|
| Flow cytometry (fixed cells) | 1–3 µg/1×106 cells (Human) |
| ELISA | 0.1–0.5 µg/mL |
Immunogen
Recombinant human PANX3 fragment (Met1–Pro392), expressed in E. coli. Sequence identity with the mouse and rat orthologs: 89% and 91.6%, respectively.
Reactivity Notes
The supplier lists reactivity with human. UniProt places pannexin-3 in the cell membrane, cell junction and endoplasmic reticulum membrane.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
