| Field | Specification |
|---|---|
| Target | |
| Alternative names | PRKC apoptosis WT1 regulator protein; Prostate apoptosis response 4 protein; Par-4; PAWR; PAR4 |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human PAR4 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 23P87 is a rabbit monoclonal antibody that recognizes PRKC apoptosis WT1 regulator protein (gene PAWR) in human, mouse and rat samples and is validated for Western blot. The predicted molecular weight is 36.6 kDa, and the supplier reports an observed band at about 40 kDa.
Par-4 (PAWR, prostate apoptosis response-4) is a pro-apoptotic protein first identified in prostate cancer cells undergoing apoptosis. It can trigger apoptosis selectively in cancer cells, in part by inhibiting NF-κB and working with WT1 to repress BCL2, and is studied as a tumor suppressor.
| Target | PRKC apoptosis WT1 regulator protein (gene PAWR; UniProt Q96IZ0, human) |
|---|---|
| Clone | 23P87 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 36.6 kDa |
| Observed MW | 40 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Immunogen
Synthetic peptide based on the sequence of human PAR4.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places PRKC apoptosis WT1 regulator protein in the cytoplasm and nucleus. Tissue expression noted by UniProt (human): Widely expressed.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
