| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Programmed cell death protein 1;Protein PD-1;hPD-1;CD279;PDCD1;PD1; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthesized peptide derived from human PD1 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
Anti-PD1 PDCD1 Rabbit Monoclonal Antibody is an antibody targeting PDCD1. Common applications include IHC. Key specifications include host: Rabbit; clonality: Monoclonal; clone: Clone: BEG-16; isotype: Rabbit IgG; reactivity: Human; observed MW: 70 kDa; calculated MW: 31647 MW.
Boster Bio Anti-PD1 PDCD1 Rabbit Monoclonal Antibody catalog # M00178-1. Tested in IHC application. This antibody reacts with Human.
Key elements and design rationale
- Target: PDCD1 — Programmed cell death protein 1
- Antibody format: Host: Rabbit; Clonality: Monoclonal; Clone: Clone: BEG-16; Isotype: Rabbit IgG
- Species reactivity: Human
- Molecular weight guidance: Observed: 70 kDa; Calculated: 31647 MW
Biological background
Protein function (datasheet): Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen- specific manner. Possible cell death inducer, in association with other factors. .
Cellular localization (datasheet): Membrane; Single-pass type I membrane protein.
Tissue details (datasheet): Brain, heart, placenta, pancreas and skeletal muscle. Expressed to a lesser extent in lung, liver and kidney.
Research relevance and current trends
- Commonly studied in contexts related to Protein Phosphorylation,Ser/Thr Kinases,Signal Transduction.
- Supports comparative expression analysis across conditions, genotypes, or treatments when paired with appropriate controls.
- Useful for confirming target presence and subcellular distribution using orthogonal readouts (e.g., microscopy vs. immunoblotting).
Common research applications
- Immunohistochemistry (IHC): Assess tissue distribution and cell-type patterns; interpret staining with appropriate negative controls and antigen context.
Notes for experimental interpretation
- Consider isoforms, post-translational modifications, and processing that can shift apparent molecular weight or localization.
- Use appropriate positive and negative controls (e.g., KO/KD, blocking peptide, or isotype controls) to support specificity interpretation.
As a monoclonal antibody, this reagent is expected to recognize a defined epitope, which can support consistency across lots when epitope accessibility is preserved.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
