| Field | Specification |
|---|---|
| Target | |
| Alternative names | Period circadian protein homolog 2; hPER2; Circadian clock protein PERIOD 2; PER2; KIAA0347 |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human PER2 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 23P14 is a rabbit monoclonal antibody that recognizes period circadian protein homolog 2 (gene PER2) in human samples and is validated for Western blot, ICC/IF and flow cytometry. The predicted molecular weight is 136.6 kDa, and the supplier reports an observed band at about 137 kDa.
PER2 (Period 2) is a core repressor of the circadian clock that forms complexes with cryptochromes and casein kinase 1 to inhibit CLOCK-BMAL1 transcription. Its timed phosphorylation and degradation help set the length of the daily cycle, and a PER2 mutation causes familial advanced sleep phase syndrome, so it is a central protein in circadian research.
| Target | Period circadian protein homolog 2 (gene PER2; UniProt O15055, human) |
|---|---|
| Clone | 23P14 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 136.6 kDa |
| Observed MW | 137 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunocytochemistry / Immunofluorescence | 1:50–1:200 |
| Flow cytometry | 1:50 |
Immunogen
Synthetic peptide based on the sequence of human PER2.
Reactivity Notes
The supplier lists reactivity with human. Tissue expression noted by UniProt (human): Widely expressed.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
