| Field | Specification |
|---|---|
| Target | |
| Alternative names | N-acetylmuramoyl-L-alanine amidase; Peptidoglycan recognition protein 2; Peptidoglycan recognition protein long; PGRP-L; PGLYRP2; PGLYRPL; PGRPL |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived human PGLYRP2 recombinant protein (Position: D198-Q524). Human PGLYRP2 shares 79.2% amino acid (aa) sequence identity with mouse PGLYRP2. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody recognizes N-acetylmuramoyl-L-alanine amidase (gene PGLYRP2) in human, mouse and rat samples and is validated for Western blot, flow cytometry and ELISA.
PGLYRP2 is a peptidoglycan recognition protein with N-acetylmuramoyl-L-alanine amidase activity, produced mainly by the liver and secreted into blood. It cuts bacterial peptidoglycan into fragments that no longer stimulate inflammation, acting as a scavenger rather than directly killing bacteria, and it is studied in innate immunity.
| Target | N-acetylmuramoyl-L-alanine amidase (gene PGLYRP2; UniProt Q96PD5, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.1–0.25 µg/mL (Human, Mouse, Rat) |
|---|---|
| Flow cytometry (fixed cells) | 1–3 µg/1×106 cells (Human) |
| ELISA | 0.1–0.5 µg/mL |
Immunogen
Recombinant human PGLYRP2 fragment (Asp198–Gln524), expressed in E. coli. Sequence identity with the mouse ortholog: 79.2%.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt describes N-acetylmuramoyl-L-alanine amidase as secreted and also located in the membrane. Tissue expression noted by UniProt (human): Strongly expressed in liver and fetal liver, and secreted into serum.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
