| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Transcription factor AP-1;Activator protein 1;AP1;Proto-oncogene c-Jun;V-jun avian sarcoma virus 17 oncogene homolog;p39;JUN; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthesized peptide derived from human Phospho-c-Jun (S73)+JunD (S100) |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Target | |
| UniProt # |
Boster Bio Anti-Phospho-c-Jun (S73)+JunD (S100) Rabbit Monoclonal Antibody catalog # P02038-2. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse.
Gene: Transcription factor AP-1 | Target: JUN/JUND | Function: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306). . | Research areas: Cancer,2339,Domain Families,Epigenetics and Nuclear Signaling,Hlh/Leucine Zipper,Immunology,Innate Immunity,Nuclear Signaling Pathways,Oncoproteins,Oncoproteins/Suppressors,Signal Transduction,Signaling Pathway,TLR Signaling,Transcription,Transcription Factors
Host: Rabbit | Clonality/Clone: Monoclonal / Clone: 30J61 | Isotype: IgG | Reactivity: Human,Mouse | Immunogen: A synthesized peptide derived from human Phospho-c-Jun (S73)+JunD (S100) | Concentration: 0.5mg/ml | Purification: Affinity-chromatography
Applications: WB, IHC, IP
Observed MW: 38 kDa, 42 kDa, 45 kDa | Calculated MW: 35676 MW
Cellular localization: Nucleus.
Tissue details: Expressed in brain, and to a lesser extent in lung, kidney and testis.
Phospho site(s): S73, S100
Status: Active
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