| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Eukaryotic translation initiation factor 2-alpha kinase 4;2.7.11.1;GCN2-like protein;EIF2AK4;GCN2, KIAA1338; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthesized peptide derived from human Phospho-GCN2 (T899) |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Target | |
| UniProt # |
Overview
Anti-Phospho-GCN2 (T899) EIF2AK4 Rabbit Monoclonal Antibody is an antibody targeting EIF2AK4. Common applications include WB. Key specifications include host: Rabbit; clonality: Monoclonal; clone: Clone: ABH-5; isotype: Rabbit IgG; reactivity: Human; observed MW: 39 kDa; calculated MW: 186911 MW.
Boster Bio Anti-Phospho-GCN2 (T899) EIF2AK4 Rabbit Monoclonal Antibody catalog # P01172. Tested in WB application. This antibody reacts with Human.
Key elements and design rationale
- Target: EIF2AK4 — Eukaryotic translation initiation factor 2-alpha kinase 4
- Antibody format: Host: Rabbit; Clonality: Monoclonal; Clone: Clone: ABH-5; Isotype: Rabbit IgG
- Species reactivity: Human
- Molecular weight guidance: Observed: 39 kDa; Calculated: 186911 MW
- Phospho site(s): T899
Biological background
Protein function (datasheet): Can phosphorylate the alpha subunit of EIF2 and may mediate translational control. .
Cellular localization (datasheet): Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export. .
Tissue details (datasheet): Widely expressed. Expressed in the lung in smooth muscle cells of the pulmonary vessel wall, interstitial tissue and macrophages. .
Research relevance and current trends
- Commonly studied in contexts related to DNA/RNA,Epigenetics and Nuclear Signaling,Protein Phosphorylation,Ser/Thr Kinases,Signal Transduction,Translation.
- Supports comparative expression analysis across conditions, genotypes, or treatments when paired with appropriate controls.
- Useful for confirming target presence and subcellular distribution using orthogonal readouts (e.g., microscopy vs. immunoblotting).
Common research applications
- Western blot (WB): Compare relative target abundance and apparent size/isoforms across samples; interpret bands in light of expected MW and potential PTMs.
Notes for experimental interpretation
- Consider isoforms, post-translational modifications, and processing that can shift apparent molecular weight or localization.
- Use appropriate positive and negative controls (e.g., KO/KD, blocking peptide, or isotype controls) to support specificity interpretation.
As a monoclonal antibody, this reagent is expected to recognize a defined epitope, which can support consistency across lots when epitope accessibility is preserved.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
