| Field | Specification |
|---|---|
| Target | |
| Alternative names | Synapsin-1;Synapsin I;Syn1;Syn-1; |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human Phospho-Synapsin I (S9) |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone FCE-19 is a rabbit monoclonal antibody that recognizes synapsin-1 (gene SYN1) phosphorylated at Ser9 in human, mouse and rat samples and is validated for Western blot and IHC. The predicted molecular weight is 74.1 kDa, and the supplier reports an observed band at about 77 kDa.
Synapsin I (SYN1) is a neuronal phosphoprotein that coats synaptic vesicles and links them to the actin cytoskeleton. Its phosphorylation state controls how vesicles are held in the reserve pool and released for neurotransmission, and it also supports axon outgrowth and synapse formation. It is a widely used presynaptic marker.
| Target | Synapsin-1 (gene SYN1; UniProt P17600, human) — phosphorylated at Ser9 |
|---|---|
| Clone | FCE-19 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 74.1 kDa |
| Observed MW | 77 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
Samples with a confirmed band (WB): human brain.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic phosphopeptide around Ser9 of human synapsin I.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places synapsin-1 in the synapse, Golgi apparatus and presynapse. The samples tested by the supplier (listed above) are a practical starting point for positive controls. Because the antibody is phospho-specific, signal depends on the phosphorylation state of the sample; a phosphatase-treated lysate is a useful negative control.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
