| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | PIK3C2B; Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta; PI3K-C2-beta; PtdIns-3-kinase C2 subunit beta; EC 2.7.1.154; C2-PI3K; Phosphoinositide 3-kinase-C2-beta |
| Clonality | |
| Concentration | |
| Gene ID | |
| Host | |
| Immunogen | E.coli-derived human PIK3C2B recombinant protein (Position: R21-E1009). |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-PIK3C2B Antibody Picoband® catalog # A06732-1. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Scientific background: The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner.
Cross reactivity: No cross-reactivity with other proteins
Protein: Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta | Gene: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta | Target: PIK3C2B
Host: Rabbit | Clonality/Clone: Polyclonal | Isotype: Rabbit IgG | Reactivity: Human,Mouse | Immunogen: E.coli-derived human PIK3C2B recombinant protein (Position: R21-E1009). | Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. | Purification: Immunogen affinity purified.
Applications: WB, IHC, ICC, ELISA
Observed MW: 160-180 kDa | Calculated MW: 185 kDa
Status: Active
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