| Field | Specification |
|---|---|
| Target | |
| Alternative names | Placenta growth factor; PlGF; PGF; PGFL |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human PLGF |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 17P70 is a rabbit monoclonal antibody that recognizes placenta growth factor (gene PGF) in human samples and is validated for Western blot. The predicted molecular weight is 24.8 kDa, and the supplier reports an observed band at about 15 kDa.
Placental growth factor (PlGF, PGF) is a VEGF family member that binds VEGFR-1 (FLT1), and some isoforms also bind neuropilins. It supports angiogenesis and endothelial growth, particularly in pathological conditions, and is highly expressed in the placenta; circulating PlGF, often measured with sFlt-1, is widely studied in pregnancy research, including preeclampsia.
| Target | Placenta growth factor (gene PGF; UniProt P49763, human) |
|---|---|
| Clone | 17P70 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 24.8 kDa |
| Observed MW | 15 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Immunogen
Synthetic peptide based on the sequence of human PLGF.
Reactivity Notes
The supplier lists reactivity with human. UniProt describes placenta growth factor as a secreted protein. Tissue expression noted by UniProt (human): While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
