| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Cysteine protease ATG4B;3.4.22.-;AUT-like 1 cysteine endopeptidase;Autophagin-1;Autophagy-related cysteine endopeptidase 1;Autophagy-related protein 4 homolog B;hAPG4B;ATG4B;APG4B, AUTL1, KIAA0943; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthesized peptide derived from human Rad51D |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-Rad51D Rabbit Monoclonal Antibody catalog # M02893. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.
Protein: T-cell surface glycoprotein CD3 zeta chain | Gene: Cysteine protease ATG4B | Target: RAD51D | Function: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C- terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. . | Research areas: Cancer,Cardiovascular,Cell Biology,Cell Death,Extracellular Matrix,Invasion/Microenvironment,Metabolism,Metabolism Processes,Pathways and Processes,Proteolysis/Ubiquitin,Proteolytic Enzymes,Signal Transduction
Host: Rabbit | Clonality/Clone: Monoclonal / Clone: 28R25 | Isotype: IgG | Reactivity: Human,Mouse,Rat | Immunogen: A synthesized peptide derived from human Rad51D | Concentration: 0.5mg/ml | Purification: Affinity-chromatography
Applications: WB, IHC, IP
Observed MW: 35 kDa | Calculated MW: 44294 MW
Cellular localization: Cytoplasm .
Tissue details: Mainly expressed in the skeletal muscle, followed by brain, heart, liver and pancreas. .
Status: Active
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