| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | REST; NRSF; XBR; RE1-silencing transcription factor; Neural-restrictive silencer factor; X2 box repressor |
| Clonality | |
| Concentration | |
| Gene ID | |
| Host | |
| Immunogen | E.coli-derived human REST recombinant protein (Position: E110-E1097). Human REST shares 62.9% and 59.6% amino acid (aa) sequence identity with mouse and rat REST, respectively. |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-REST Antibody Picoband® catalog # A03852-3. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Scientific background: This gene was initially identified as a transcriptional repressor that represses neuronal genes in non-neuronal tissues. However, depending on the cellular context, this gene can act as either an oncogene or a tumor suppressor. The encoded protein is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regulator of neurogenesis. Alternatively spliced transcript variants have been described.
Cross reactivity: No cross-reactivity with other proteins
Protein: RE1-silencing transcription factor | Gene: RE1 silencing transcription factor | Target: REST
Host: Rabbit | Clonality/Clone: Polyclonal | Isotype: Rabbit IgG | Reactivity: Human | Immunogen: E.coli-derived human REST recombinant protein (Position: E110-E1097). Human REST shares 62.9% and 59.6% amino acid (aa) sequence identity with mouse and rat REST, respectively. | Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. | Purification: Immunogen affinity purified.
Applications: WB, IHC, ICC, FC, ELISA
Observed MW: 51 kDa | Calculated MW: 122 kDa
Status: Active
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