| Field | Specification |
|---|---|
| Target | |
| Alternative names | Retrotransposon-like protein 1; Mammalian retrotransposon derived protein 1; Paternally expressed gene 11 protein; Retrotransposon-derived protein PEG11; RTL1; MAR1; MART1; PEG11 |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived human RTL1 recombinant protein (Position: H446-R1327). Human RTL1 shares 68.3% amino acid (aa) sequence identity with mouse RTL1. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody detects retrotransposon-like protein 1 (gene RTL1) in human, mouse and rat samples and is validated for Western blot, flow cytometry and ELISA.
RTL1 (also called PEG11) is a paternally expressed imprinted gene derived from an ancient retrotransposon. It is required in fetal capillary endothelial cells of the placenta to maintain the fetal–maternal interface, and altered RTL1 dosage in the DLK1–DIO3 imprinted region is linked to Kagami–Ogata and Temple syndromes.
| Target | Retrotransposon-like protein 1 (gene RTL1; UniProt A6NKG5, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.25–0.5 µg/mL (Human, Mouse, Rat) |
|---|---|
| Flow cytometry (fixed cells) | 1–3 µg/1×106 cells (Human) |
| ELISA | 0.1–0.5 µg/mL |
Immunogen
Recombinant human RTL1 fragment (His446–Arg1327), expressed in E. coli. Sequence identity with the mouse ortholog: 68.3%.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places retrotransposon-like protein 1 in the membrane.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
