| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | RYK; JTK5A; Tyrosine-protein kinase RYK; EC 2.7.10.1 |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | E.coli-derived human RYK recombinant protein (Position: L66-V607). Human RYK shares 97.2% amino acid (aa) sequence identity with mouse RYK. |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-RYK Antibody Picoband® catalog # A07225-1. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Scientific background: The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Cross reactivity: No cross-reactivity with other proteins
Protein: Tyrosine-protein kinase RYK | Gene: receptor like tyrosine kinase | Target: RYK
Host: Rabbit | Clonality/Clone: Polyclonal | Isotype: Rabbit IgG | Reactivity: Human,Mouse,Rat | Immunogen: E.coli-derived human RYK recombinant protein (Position: L66-V607). Human RYK shares 97.2% amino acid (aa) sequence identity with mouse RYK. | Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. | Purification: Immunogen affinity purified.
Applications: WB, IHC, ICC, FC, ELISA
Observed MW: 75 kDa | Calculated MW: 68 kDa
Status: Active
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