| Field | Specification |
|---|---|
| Target | |
| Alternative names | Plasma protease C1 inhibitor; C1 Inh; C1Inh; C1 esterase inhibitor; C1-inhibiting factor; Serpin G1; SERPING1; C1IN; C1NH |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human SERPING1 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 25S86 is a rabbit monoclonal antibody that recognizes plasma protease C1 inhibitor (gene SERPING1) in human, mouse and rat samples and is validated for Western blot and immunoprecipitation. The predicted molecular weight is 55.2 kDa, and the supplier reports an observed band at about 100 kDa.
C1 inhibitor (SERPING1) is a plasma serpin that controls the classical complement pathway by forming inactive complexes with the proteases C1r and C1s. It also inhibits factor XIIa and plasma kallikrein, limiting bradykinin production, and inherited C1 inhibitor deficiency causes hereditary angioedema.
| Target | Plasma protease C1 inhibitor (gene SERPING1; UniProt P05155, human) |
|---|---|
| Clone | 25S86 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 55.2 kDa |
| Observed MW | 100 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunoprecipitation | 1:50 |
Samples with a confirmed band (WB): human plasma.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human SERPING1.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt describes plasma protease C1 inhibitor as a secreted protein. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
