| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | High affinity copper uptake protein 1; Copper transporter 1; hCTR1; Solute carrier family 31 member 1; SLC31A1; COPT1; CTR1 |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthetic peptide corresponding to a sequence in the middle region of human SLC31A1/CTR1, identical to the related mouse and rat sequences. |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
This antibody is intended for detection of SLC31A1 (Tumor necrosis factor-inducible gene 6 protein) in biological samples using common immunoassay formats. It is typically selected based on target identity, species reactivity, clonality/clone information, and detection modality.
Vendor notes: Boster Bio Anti-SLC31A1/CTR1 Antibody Picoband® catalog # A03447-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key elements and design rationale
- Antibody format: Rabbit Polyclonal Rabbit IgG
- Immunogen / epitope context: A synthetic peptide corresponding to a sequence in the middle region of human SLC31A1/CTR1, identical to the related mouse and rat sequences.
- Molecular weight context: reported MW: 26 kDa; calculated MW: 31203 MW
- Reactivity: Human,Mouse,Rat
- Applications: WB
As a polyclonal antibody, the reagent recognizes multiple epitopes on the target, which can improve detection robustness but may increase sensitivity to sample-dependent epitope changes.
Biological background
Tumor necrosis factor-inducible gene 6 protein; solute carrier family 31 member 1. High affinity copper uptake protein 1 (Ctr1) is a protein that in humans is encoded by the SLC31A1 gene. This gene is maped to 9q32. The protein encoded by this gene is a high-affinity copper transporter found in the cell membrane. The encoded protein functions as a homotrimer to effect the uptake of dietary copper. Functional note: High-affinity, saturable copper transporter involved in dietary copper uptake. Reported localization: Cell membrane; Localizes to the apical membrane in intestinal epithelial cells. Expression/tissue context: Found in the synovial fluid of patients with rheumatoid arthritis. .
Research relevance and current trends
- Neuroscience: Researchers commonly examine how SLC31A1 (Tumor necrosis factor-inducible gene 6 protein) relates to this theme using model systems and orthogonal readouts.
- Neurotransmission: Researchers commonly examine how SLC31A1 (Tumor necrosis factor-inducible gene 6 protein) relates to this theme using model systems and orthogonal readouts.
- Receptors / Channels: Researchers commonly examine how SLC31A1 (Tumor necrosis factor-inducible gene 6 protein) relates to this theme using model systems and orthogonal readouts.
Common research applications
- Western blotting: compare relative SLC31A1 (Tumor necrosis factor-inducible gene 6 protein) levels across conditions; band patterns may reflect isoforms and processing.
Notes for experimental interpretation
- Specificity notes: No cross reactivity with other proteins.
- Cross-reactivity: No cross-reactivity with other proteins.
- Isoforms and PTMs: Apparent size and signal patterns can differ across splice isoforms, proteolytic processing, and post-translational modifications.
- Controls: Include an isotype control (as relevant), no-primary control for imaging, and orthogonal validation such as KD/KO samples when available.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
