| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Fms-related tyrosine kinase 3 ligand ;Flt3lg ; |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | E.coli-derived human SOX7 recombinant protein (Position: K57-D343). |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
Anti-SOX7 Antibody Picoband® is an antibody for SOX7 detection raised in Rabbit (Polyclonal, Rabbit IgG), with reported reactivity: Human. Commonly used in WB, IHC, Flow Cytometry, ELISA workflows.
Key elements and design rationale
- Target: SOX7 (fms-related tyrosine kinase 3 ligand); UniProt: Q9BT81
- Antibody format: Rabbit, Polyclonal, Rabbit IgG
- Molecular weight: 43 kDa, calculated 25847 MW
- Applications: WB, IHC, Flow Cytometry, ELISA
Vendor description (summary): Boster Bio Anti-SOX7 Antibody Picoband® catalog # A05013-1.
Biological background
Biological context: SOX7 is commonly studied as part of broader pathways controlling cellular state and phenotype. Researchers often assess changes in abundance, localization, or interaction partners across experimental conditions.
Common research applications
- Western blotting (WB): Compare SOX7 levels across samples and conditions using appropriate loading and biological controls.
- Immunohistochemistry (IHC): Evaluate spatial distribution of SOX7 in tissue sections, considering fixation and antigen retrieval effects.
- Flow cytometry: Quantify SOX7-positive populations in single-cell suspensions with appropriate gating and controls.
- ELISA: Use antibody-based detection formats to assess antigen presence or binding in plate-based assays.
Notes for experimental interpretation
- Account for isoforms, post-translational modifications, and sample-specific processing that can shift apparent molecular weight or epitope accessibility.
- Use positive/negative biological controls where possible (e.g., known-expressing cells/tissues, knockdown/knockout models) and include appropriate secondary-only/isotype controls for imaging workflows.
Additional product notes (from provided fields)
- Background: SOX7 belongs to SOX gene family and SOX proteins are transcription factors with critical roles in the regulation of diverse developmental processes. This gene is mapped to 8p23.1. SOX7 gene contains at least 2 exons. In cotransfected 293 cells, Sox7 reduced Wnt (see WNT1)/beta-catenin (see CTNNB1)- stimulated transcription. SOX7 is a potent activator of FGF3 transcription. It not only plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium but also blocks further differentiation into blood precursors. And it may be required for the survival of both hematopoietic and endothelial precursors during specification.
- Cross reactivity: No cross-reactivity with other proteins.
- Research category: Angiogenesis,Cardiovascular,Cytokines,Immunology,Innate Immunity
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
