| Field | Specification |
|---|---|
| Target | |
| Alternative names | Transcription factor Sp1;SP1;TSFP1; |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human SP1 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone AOOC-19 is a rabbit monoclonal antibody that recognizes transcription factor Sp1 in human samples and is validated for Western blot, IHC and ICC/IF. The predicted molecular weight is 80.7 kDa, and the supplier reports an observed band at about 90 kDa.
Transcription factor Sp1 (SP1) is a zinc finger protein that binds GC-rich promoter elements and regulates a very large number of genes involved in growth, apoptosis, differentiation and immune responses. Its activity is tuned by phosphorylation, acetylation, glycosylation and other modifications, and it is one of the most studied general transcription regulators.
| Target | Transcription factor Sp1 (gene SP1; UniProt P08047, human) |
|---|---|
| Clone | AOOC-19 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 80.7 kDa |
| Observed MW | 90 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
| Immunocytochemistry / Immunofluorescence | 1:50–1:200 |
Immunogen
Synthetic peptide based on the sequence of human SP1.
Reactivity Notes
The supplier lists reactivity with human. UniProt places transcription factor Sp1 in the nucleus and cytoplasm. Tissue expression noted by UniProt (human): Up-regulated in adenocarcinomas of the stomach (at protein level).
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
