| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | SPO11; Meiotic recombination protein SPO11; EC 5.6.2.2; Cancer/testis antigen 35; CT35 |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | E.coli-derived human SPO11 recombinant protein (Position: R40-D326). Human SPO11 shares 83.3% amino acid (aa) sequence identity with mouse SPO11. |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-SPO11 Antibody Picoband® catalog # A04719-3. Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Scientific background: Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described.
Cross reactivity: No cross-reactivity with other proteins
Protein: Meiotic recombination protein SPO11 | Gene: SPO11 initiator of meiotic double strand breaks | Target: SPO11
Host: Rabbit | Clonality/Clone: Polyclonal | Isotype: Rabbit IgG | Reactivity: Human,Mouse,Rat | Immunogen: E.coli-derived human SPO11 recombinant protein (Position: R40-D326). Human SPO11 shares 83.3% amino acid (aa) sequence identity with mouse SPO11. | Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. | Purification: Immunogen affinity purified.
Applications: WB, IHC, IF, ICC, ELISA
Observed MW: 70 kDa | Calculated MW: 45 kDa
Status: Active
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.