| Field | Specification |
|---|---|
| Target | |
| Alternative names | Serine/arginine-rich splicing factor 6; Pre-mRNA-splicing factor SRP55; Splicing factor, arginine/serine-rich 6; SRSF6; SFRS6; SRP55 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human SR protein repeat |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 27S70 is a rabbit monoclonal antibody that recognizes serine/arginine-rich splicing factor 6 (gene SRSF6) in human samples and is validated for Western blot and IHC. The predicted molecular weight is 39.6 kDa, and the supplier reports an observed band at about 38–45 kDa.
Serine/arginine-rich splicing factor 6 (SRSF6, also called SRp55) is an SR protein that takes part in constitutive splicing and in choosing alternative splice sites. It regulates exon 10 splicing of MAPT/tau and splicing of tenascin C, and it influences keratinocyte proliferation and wound healing.
| Target | Serine/arginine-rich splicing factor 6 (gene SRSF6; UniProt Q13247, human) |
|---|---|
| Clone | 27S70 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 39.6 kDa |
| Observed MW | 38–45 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
Samples with a confirmed band (WB): K562 cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human SR protein repeat.
Reactivity Notes
The supplier lists reactivity with human. UniProt places serine/arginine-rich splicing factor 6 in the nucleus and nucleus speckle. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
