| Field | Specification |
|---|---|
| Target | |
| Alternative names | Striatin-3; Cell cycle autoantigen SG2NA; S/G2 antigen; STRN3; GS2NA; SG2NA |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived human STRN3 recombinant protein (Position: D243-H690). Human STRN3 shares 95.2% and 95.1% amino acid (aa) sequence identity with mouse and rat STRN3, respectively. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody recognizes striatin-3 (gene STRN3) in human, mouse and rat samples and is validated for Western blot, flow cytometry and ELISA.
Striatin-3 (STRN3) is a calmodulin-binding scaffold protein that serves as a central subunit of STRIPAK complexes. By recruiting the phosphatase PP2A together with signaling kinases such as MST family members, it regulates Hippo, MAPK and cytoskeletal pathways involved in cell growth, differentiation and apoptosis.
| Target | Striatin-3 (gene STRN3; UniProt Q13033, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.1–0.25 µg/mL (Human, Mouse, Rat) |
|---|---|
| Flow cytometry (fixed cells) | 1–3 µg/1×106 cells (Human) |
| ELISA | 0.1–0.5 µg/mL |
Immunogen
Recombinant human STRN3 fragment (Asp243–His690), expressed in E. coli. Sequence identity with the mouse and rat orthologs: 95.2% and 95.1%, respectively.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places striatin-3 in the cytoplasm and membrane.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
