| Field | Specification |
|---|---|
| Target | |
| Alternative names | SUN domain-containing protein 1; Protein unc-84 homolog A; Sad1/unc-84 protein-like 1; SUN1; KIAA0810; UNC84A |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human SUN1 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 20S09 is a rabbit monoclonal antibody that recognizes SUN domain-containing protein 1 (gene SUN1) in human samples and is validated for Western blot, IHC, ICC/IF and flow cytometry. The predicted molecular weight is 90.1 kDa, and the supplier reports an observed band at about 98 kDa.
SUN1 is an inner nuclear membrane protein that partners with KASH-domain nesprins in the outer membrane to form the LINC complex. This bridge connects the nuclear lamina to the cytoskeleton, transmitting mechanical force, positioning the nucleus and attaching telomeres to the nuclear envelope during meiosis, which is essential for fertility.
| Target | SUN domain-containing protein 1 (gene SUN1; UniProt O94901, human) |
|---|---|
| Clone | 20S09 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 90.1 kDa |
| Observed MW | 98 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
| Immunocytochemistry / Immunofluorescence | 1:50–1:200 |
| Flow cytometry | 1:50 |
Samples with a confirmed band (WB): Ramos cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human SUN1.
Reactivity Notes
The supplier lists reactivity with human. UniProt places SUN domain-containing protein 1 in the nucleus inner membrane. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
