| Field | Specification |
|---|---|
| Target | |
| Alternative names | Extracellular superoxide dismutase [Cu-Zn]; EC-SOD; SOD3 |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human Superoxide Dismutase 3 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 17S81 is a rabbit monoclonal antibody that recognizes extracellular superoxide dismutase (gene SOD3) in human samples and is validated for Western blot and IHC. The predicted molecular weight is 25.9 kDa, and the supplier reports an observed band at about 26 kDa.
Extracellular superoxide dismutase (SOD3, EC-SOD) is a secreted copper-zinc enzyme that removes superoxide radicals outside cells, converting them to hydrogen peroxide. By limiting the reaction of superoxide with nitric oxide, it helps preserve nitric oxide signaling in blood vessels, and it is studied in vascular biology, lung injury and inflammation.
| Target | Extracellular superoxide dismutase (gene SOD3; UniProt P08294, human) |
|---|---|
| Clone | 17S81 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 25.9 kDa |
| Observed MW | 26 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
Immunogen
Synthetic peptide based on the sequence of human superoxide Dismutase 3.
Reactivity Notes
The supplier lists reactivity with human. UniProt describes extracellular superoxide dismutase as secreted and also located in the Golgi apparatus and vesicle. Tissue expression noted by UniProt (human): Expressed in blood vessels, heart, lung, kidney and placenta.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
