| Field | Specification |
|---|---|
| Target | |
| Alternative names | Talin-2;TLN2;KIAA0320; |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human Talin 2 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone BAG-20 is a rabbit monoclonal antibody that recognizes talin-2 (gene TLN2) in human, mouse and rat samples and is validated for Western blot. The predicted molecular weight is 271.6 kDa, and the supplier reports an observed band at about 270 kDa.
Talin-2 (TLN2) is a paralog of talin-1 that links integrins to the actin cytoskeleton at focal adhesions and other adhesion structures. It is enriched in muscle and brain, and it can recruit and activate the lipid kinase PIP5K1C. Talin-2 is studied in cell adhesion, muscle attachment and synaptic biology.
| Target | Talin-2 (gene TLN2; UniProt Q9Y4G6, human) |
|---|---|
| Clone | BAG-20 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 271.6 kDa |
| Observed MW | 270 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Samples with a confirmed band (WB): expression HeLa cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human talin 2.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places talin-2 in the cytoplasm, cell junction, synapse and cell membrane. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.