| Field | Specification |
|---|---|
| Target | |
| Alternative names | C-C motif chemokine ;Ccl17 ;ABCD-2 , TARC ;mCG_12286 ; |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived mouse TARC recombinant protein (Position: A34-P103). Mouse TARC shares 71% amino acid (aa) sequence identity with human TARC. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody detects C-C motif chemokine 17 (gene Ccl17) in mouse samples and is validated for Western blot and ELISA.
CCL17 (also called TARC) is a C-C chemokine that binds the receptor CCR4 and preferentially attracts Th2 cells and regulatory T cells. It is produced by dendritic cells and other cells and is elevated in allergic diseases such as atopic dermatitis, where it is commonly measured as a disease activity marker.
| Target | C-C motif chemokine 17 (gene Ccl17; UniProt Q9WUZ6, mouse) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Mouse |
| Form | Lyophilized |
| Formulation | Per vial: 0.9 mg NaCl; 0.2 mg Na2HPO4; 0.05 mg NaN3; plus stabilizers |
| Observed MW | 34 kDa |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.1–0.5 µg/mL (Mouse) |
|---|---|
| ELISA | 0.1–0.5 µg/mL |
Conditions in the example images (WB): 5–20% gradient SDS-PAGE, transfer to nitrocellulose membrane, blocking in 5% non-fat milk, primary antibody at 0.5 µg/mL overnight at 4 °C, HRP-conjugated secondary antibody at 1:10000, ECL detection.
Immunogen
Recombinant mouse TARC fragment (Ala34–Pro103), expressed in E. coli. Sequence identity with the human ortholog: 71%.
Reactivity Notes
The supplier lists reactivity with mouse. UniProt describes C-C motif chemokine 17 as a secreted protein. Tissue expression noted by UniProt (mouse): Expressed in primary and secondary lymphoid organs, where it is specifically produced by a subset of dendritic cells.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Liang Song et al. (2026) CCL17-neutralizing and esterase-responsive core-shell microgels for endogenous Tregs recruitment and functional enhancement in myocardial infarction. Bioactive Materials. 10.1016/j.bioactmat.2026.06.012
