| Field | Specification |
|---|---|
| Target | |
| Alternative names | T-box brain protein 1;T-brain-1;TBR-1;TES-56;TBR1; |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human TBR1 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone AOEC-20 is a rabbit monoclonal antibody that recognizes T-box brain protein 1 (gene TBR1) in human, mouse and rat samples and is validated for Western blot. The predicted molecular weight is 74.1 kDa, and the supplier reports an observed band at about 74 kDa.
T-box brain protein 1 (TBR1) is a T-box transcription factor expressed in postmitotic excitatory neurons of the developing cortex. It helps set cortical layer and areal identity and directs axon projections, in part by repressing FEZF2 in deep-layer neurons, and TBR1 variants are associated with autism and intellectual disability.
| Target | T-box brain protein 1 (gene TBR1; UniProt Q16650, human) |
|---|---|
| Clone | AOEC-20 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 74.1 kDa |
| Observed MW | 74 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Samples with a confirmed band (WB): human fetal brain.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human TBR1.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places T-box brain protein 1 in the nucleus. Tissue expression noted by UniProt (human): Brain. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
