| Field | Specification |
|---|---|
| Target | |
| Alternative names | Tenascin;TN;Cytotactin;GMEM;GP 150-225;Glioma-associated-extracellular matrix antigen;Hexabrachion;JI;Myotendinous antigen;Neuronectin;Tenascin-C;TN-C;TNC;HXB; |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human Tenascin C |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone CEG-20 is a rabbit monoclonal antibody that recognizes tenascin (gene TNC) in human samples and is validated for Western blot. The predicted molecular weight is 240.9 kDa, and the supplier reports an observed band at about 241 kDa.
Tenascin-C (TNC) is a large hexameric extracellular matrix glycoprotein that is abundant during development and largely re-expressed during injury, inflammation and tumor growth. It modulates cell adhesion and migration through integrins and other receptors and guides neuronal and axonal migration in the nervous system. Tenascin-C is studied in wound healing, tissue remodeling, neural development and the tumor microenvironment.
| Target | Tenascin (gene TNC; UniProt P24821, human) |
|---|---|
| Clone | CEG-20 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 240.9 kDa |
| Observed MW | 241 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Samples with a confirmed band (WB): human fetal brain, human fetal kidney.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human tenascin C.
Reactivity Notes
The supplier lists reactivity with human. Tissue expression noted by UniProt (human): Detected in fibroblasts (at protein level). The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Jiaxuan Zhao et al. (2025) GJB2 promotes ovarian cancer progression and cisplatin resistance by upregulating TNC expression. Biochimica et Biophysica ACTA-Molecular Cell Research. 10.1016/j.bbamcr.2025.120058
