| Field | Specification |
|---|---|
| Target | |
| Alternative names | TGF-beta receptor type-2;TGFR-2;2.7.11.30;TGF-beta type II receptor;Transforming growth factor-beta receptor type II;TGF-beta receptor type II;TbetaR-II;TGFBR2; |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human TGF beta Receptor II |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone ABFE-20 is a rabbit monoclonal antibody that recognizes TGF-beta receptor type-2 (gene TGFBR2) in human samples and is validated for Western blot. The predicted molecular weight is 64.6 kDa, and the supplier reports an observed band at about 80 kDa.
TGF-β receptor type 2 (TGFBR2) is a constitutively active transmembrane serine/threonine kinase that binds TGF-β1, β2 and β3 directly. Ligand binding lets it recruit and phosphorylate TGFBR1, launching SMAD signaling, and TGFBR2 mutations are linked to Loeys-Dietz syndrome and to some cancers.
| Target | TGF-beta receptor type-2 (gene TGFBR2; UniProt P37173, human) |
|---|---|
| Clone | ABFE-20 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 64.6 kDa |
| Observed MW | 80 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Immunogen
Synthetic peptide based on the sequence of human TGF beta Receptor II.
Reactivity Notes
The supplier lists reactivity with human. UniProt places TGF-beta receptor type-2 in the cell membrane, membrane raft and SUBCELLULAR LOCATION:.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
