| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | TIRAP; MAL; Toll/interleukin-1 receptor domain-containing adapter protein; TIR domain-containing adapter protein; Adaptor protein Wyatt; MyD88 adapter-like protein; MyD88-2 |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | E.coli-derived human TIRAP recombinant protein (Position: P10-S221). Human TIRAP shares 74% amino acid (aa) sequence identity with mouse TIRAP. |
| Isotype | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-TIRAP Antibody catalog # A00950-1. Tested in IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human.
Scientific background: The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.
Cross reactivity: No cross-reactivity with other proteins
Protein: Toll/interleukin-1 receptor domain-containing adapter protein | Gene: TIR domain containing adaptor protein | Target: TIRAP
Host: Rabbit | Clonality/Clone: Polyclonal | Isotype: Rabbit IgG | Reactivity: Human | Immunogen: E.coli-derived human TIRAP recombinant protein (Position: P10-S221). Human TIRAP shares 74% amino acid (aa) sequence identity with mouse TIRAP. | Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. | Purification: Immunogen affinity purified.
Applications: WB, IHC, ICC, FC, ELISA
Status: Active
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
