| Field | Specification |
|---|---|
| Target | |
| Alternative names | Tomoregulin-2; TR-2; Hyperplastic polyposis protein 1; Transmembrane protein with EGF-like and two follistatin-like domains; TMEFF2; HPP1; TENB2; TPEF |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human TMEFF2 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 24T45 is a rabbit monoclonal antibody that recognizes tomoregulin-2 (gene TMEFF2) in human samples and is validated for Western blot, IHC, ICC/IF and flow cytometry. The predicted molecular weight is 41.4 kDa, and the supplier reports an observed band at about 41 kDa.
Tomoregulin-2 (TMEFF2) is a transmembrane protein with EGF-like and follistatin-like domains, expressed mainly in brain and prostate. It has been proposed to act as a survival factor for certain neurons, and its shed ectodomain can promote cancer cell growth. TMEFF2 is studied in prostate cancer and neurobiology.
| Target | Tomoregulin-2 (gene TMEFF2; UniProt Q9UIK5, human) |
|---|---|
| Clone | 24T45 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 41.4 kDa |
| Observed MW | 41 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
| Immunocytochemistry / Immunofluorescence | 1:50–1:200 |
| Flow cytometry | 1:50 |
Samples with a confirmed band (WB): LnCaP cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human TMEFF2.
Reactivity Notes
The supplier lists reactivity with human. Tissue expression noted by UniProt (human): Highly expressed in adult and fetal brain, spinal cord and prostate. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
