| Field | Specification |
|---|---|
| Target | |
| Alternative names | Tropomodulin-2; Neuronal tropomodulin; N-Tmod; TMOD2; NTMOD |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human TMOD2 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 24T81 is a rabbit monoclonal antibody that recognizes tropomodulin-2 (gene TMOD2) in human, mouse and rat samples and is validated for Western blot, IHC, ICC/IF and immunoprecipitation. The predicted molecular weight is 39.6 kDa, and the supplier reports an observed band at about 40 kDa.
Tropomodulin-2 (TMOD2) is a neuron-enriched member of the tropomodulin family of actin pointed-end capping proteins. Working with tropomyosin, it blocks elongation and depolymerization at the actin filament pointed end. TMOD2 is studied in neuronal actin dynamics, synaptic structure and learning and memory.
| Target | Tropomodulin-2 (gene TMOD2; UniProt Q9NZR1, human) |
|---|---|
| Clone | 24T81 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 39.6 kDa |
| Observed MW | 40 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
| Immunocytochemistry / Immunofluorescence | 1:50–1:200 |
| Immunoprecipitation | 1:50 |
Samples with a confirmed band (WB): SH-SY5Y cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human TMOD2.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places tropomodulin-2 in the cytoplasm. Tissue expression noted by UniProt (human): Neuronal-tissue specific. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
