| Field | Specification |
|---|---|
| Target | |
| Alternative names | Transportin-3; Importin-12; Imp12; Transportin-SR; TRN-SR; TNPO3; IPO12 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human TNPO3 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 19T91 is a rabbit monoclonal antibody that recognizes transportin-3 (gene TNPO3) in human, mouse and rat samples and is validated for Western blot, IHC and ICC/IF. The predicted molecular weight is 104.2 kDa, and the supplier reports an observed band at about 100 kDa.
Transportin-3 (TNPO3) is a nuclear import receptor of the importin-β family. It recognizes phosphorylated serine/arginine-rich (SR) splicing factors and CPSF6 and carries them into the nucleus, where binding of Ran-GTP releases the cargo. TNPO3 is also an important host factor for HIV-1 infection and is studied in RNA processing and virology.
| Target | Transportin-3 (gene TNPO3; UniProt Q9Y5L0, human) |
|---|---|
| Clone | 19T91 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 104.2 kDa |
| Observed MW | 100 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
| Immunocytochemistry / Immunofluorescence | 1:50–1:200 |
Immunogen
Synthetic peptide based on the sequence of human TNPO3.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places transportin-3 in the nucleus envelope and cytoplasm. Tissue expression noted by UniProt (human): Expressed in skeletal muscle.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
