| Field | Specification |
|---|---|
| Target | |
| Alternative names | Tensin-4; C-terminal tensin-like protein; TNS4; CTEN |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human TNS4 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 30T19 is a rabbit monoclonal antibody that recognizes tensin-4 (gene TNS4) in human, mouse and rat samples and is validated for Western blot. The predicted molecular weight is 76.8 kDa, and the supplier reports an observed band at about 90 kDa.
Tensin-4 (TNS4, also called CTEN) is a short member of the tensin family that lacks the actin-binding region of other tensins. After EGF stimulation it displaces tensin-3 from integrin β1, promoting adhesion turnover and cell migration, and it also stabilizes EGFR and MET. TNS4 is frequently studied in cancer cell migration and invasion.
| Target | Tensin-4 (gene TNS4; UniProt Q8IZW8, human) |
|---|---|
| Clone | 30T19 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 76.8 kDa |
| Observed MW | 90 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Samples with a confirmed band (WB): HepG2 cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human TNS4.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places tensin-4 in the cell junction and cytoplasm. Tissue expression noted by UniProt (human): Expressed at low levels in colon (at protein level). The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
