| Field | Specification |
|---|---|
| Target | |
| Alternative names | Transferrin receptor protein 2; TfR2 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human Transferrin Receptor 2 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 19T07 is a rabbit monoclonal antibody that recognizes transferrin receptor protein 2 (gene TFR2) in human samples and is validated for Western blot and IHC. The predicted molecular weight is 88.8 kDa, and the supplier reports an observed band at about 100 kDa.
Transferrin receptor 2 (TFR2) is a transferrin-binding membrane protein expressed mainly in hepatocytes and erythroid precursors. Rather than being a major iron importer, it acts as an iron sensor that helps regulate hepcidin, and TFR2 mutations cause type 3 hereditary hemochromatosis.
| Target | Transferrin receptor protein 2 (gene TFR2; UniProt Q9UP52, human) |
|---|---|
| Clone | 19T07 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 88.8 kDa |
| Observed MW | 100 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
Samples with a confirmed band (WB): HepG2 cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human transferrin Receptor 2.
Reactivity Notes
The supplier lists reactivity with human. UniProt places transferrin receptor protein 2 in the cell membrane and SUBCELLULAR LOCATION:. Tissue expression noted by UniProt (human): Predominantly expressed in liver. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
