| Field | Specification |
|---|---|
| Target | |
| Alternative names | Transient receptor potential cation channel subfamily M member 8; Long transient receptor potential channel 6; LTrpC-6; LTrpC6; Transient receptor potential p8; Trp-p8; TRPM8; TRPP8 |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human TRPM8 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone ADBI-20 is a rabbit monoclonal antibody that recognizes transient receptor potential cation channel subfamily M member 8 (gene TRPM8) in human and mouse samples and is validated for Western blot and ICC/IF. The predicted molecular weight is 127.7 kDa, and the supplier reports an observed band at about 128 kDa.
TRPM8 is the main cold- and menthol-activated ion channel of sensory neurons. It opens at cool temperatures and in response to cooling compounds such as menthol and icilin, allowing cation entry that signals cold, and it is also involved in regulating tear secretion. It is studied in thermosensation, cold pain and prostate biology.
| Target | Transient receptor potential cation channel subfamily M member 8 (gene TRPM8; UniProt Q7Z2W7, human) |
|---|---|
| Clone | ADBI-20 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human, Mouse |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 127.7 kDa |
| Observed MW | 128 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunocytochemistry / Immunofluorescence | 1:50–1:200 |
Immunogen
Synthetic peptide based on the sequence of human TRPM8.
Reactivity Notes
The supplier lists reactivity with human and mouse. UniProt places transient receptor potential cation channel subfamily M member 8 in the cell membrane, membrane raft and endoplasmic reticulum membrane. Tissue expression noted by UniProt (human): Expressed in prostate.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
