| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | TTL; Tubulin--tyrosine ligase; TTL; EC 6.3.2.25 |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | E.coli-derived human TTL recombinant protein (Position: N104-L377). Human TTL shares 95.3% and 95.6% amino acid (aa) sequence identity with mouse and rat TTL, respectively. |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-TTL Antibody Picoband® catalog # A06710. Tested in WB, ELISA applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Scientific background: TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]).
Cross reactivity: No cross-reactivity with other proteins
Protein: Tubulin--tyrosine ligase | Gene: tubulin tyrosine ligase | Target: TTL
Host: Rabbit | Clonality/Clone: Polyclonal | Isotype: Rabbit IgG | Reactivity: Mouse,Rat | Immunogen: E.coli-derived human TTL recombinant protein (Position: N104-L377). Human TTL shares 95.3% and 95.6% amino acid (aa) sequence identity with mouse and rat TTL, respectively. | Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. | Purification: Immunogen affinity purified.
Applications: WB, IHC, ICC, ELISA
Observed MW: 43 kDa | Calculated MW: 43 kDa
Status: Active
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