| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Keratin, type I cytoskeletal 13;Cytokeratin-13;CK-13;Keratin-13;K13;KRT13; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthesized peptide derived from human ULBP1 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-ULBP1 Rabbit Monoclonal Antibody catalog # M04323. Tested in WB application. This antibody reacts with Human.
Protein: T-cell surface glycoprotein CD3 zeta chain | Gene: Keratin, type I cytoskeletal 13 | Target: ULBP1 | Function: Serine/threonine-protein kinase involved in various processes such as neuronal proliferation, differentiation, migration and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress- activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK10/JNK3. In turn, MAPK10/JNK3 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity. Plays regulatory roles in the signaling pathways during neuronal apoptosis. Phosphorylates the neuronal microtubule regulator STMN2. Acts in the regulation of the beta-amyloid precursor protein/APP signaling during neuronal differentiation by phosphorylating APP. Participates also in neurite growth in spiral ganglion neurons. Phosphorylates the CLOCK-ARNTL/BMAL1 heterodimer and plays a role in the photic regulation of the circadian clock (PubMed:22441692). . | Research areas: DNA/RNA,DNA Synthesis,Epigenetics and Nuclear Signaling,Metabolic Signaling Pathways,Metabolism,Nucleotide Metabolism,Pathways and Processes
Host: Rabbit | Clonality/Clone: Monoclonal / Clone: 30U90 | Isotype: IgG | Reactivity: Human | Immunogen: A synthesized peptide derived from human ULBP1 | Concentration: 0.5mg/ml | Purification: Affinity-chromatography
Applications: WB
Observed MW: 36 kDa | Calculated MW: 49588 MW
Cellular localization: Cytoplasm . Membrane ; Lipid-anchor . Nucleus . Mitochondrion . Palmitoylation regulates MAPK10 trafficking to cytoskeleton. Recruited to the mitochondria in the presence of SARM1 (By similarity). .
Tissue details: Expressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta. .
Status: Active
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