| Field | Specification |
|---|---|
| Target | |
| Alternative names | Vascular endothelial growth factor A;VEGF-A;Vascular permeability factor;VPF;VEGFA;VEGF; |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived human VEGF recombinant protein (Position: A27-R191). Human VEGF shares 78% amino acid (aa) sequence identity with both mouse and rat VEGF. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody detects vascular endothelial growth factor A, long form (gene VEGFA) in human, mouse and rat samples and is validated for Western blot, IHC and flow cytometry.
VEGF-A is the main vascular endothelial growth factor that drives angiogenesis. Produced in response to hypoxia, it binds VEGFR1 and VEGFR2 on endothelial cells to promote their proliferation, migration and survival and to increase vascular permeability. VEGF-A is widely studied in vascular development, wound healing, eye disease and tumor angiogenesis.
| Target | Vascular endothelial growth factor A, long form (gene VEGFA; UniProt P15692, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Observed MW | 18, 27 kDa |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | Not specified by the supplier |
|---|---|
| Immunohistochemistry | Not specified by the supplier |
| Flow cytometry | Not specified by the supplier |
Immunogen
Recombinant human VEGF fragment (Ala27–Arg191), expressed in E. coli. Sequence identity with the mouse and rat orthologs: 78%.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places vascular endothelial growth factor A, long form in the [N-VEGF]: Cytoplasm and nucleus. Tissue expression noted by UniProt (human): Higher expression in pituitary tumors than the pituitary gland...
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Lantian Ma et al. (2026) Photocrosslinked organic-inorganic protein hydrogel with built-in nanoclusters for spatial biomineralization and enhanced osteogenesis. Nano Today. 10.1016/j.nantod.2026.103031
Xiang Zeng et al. (2015) Integration of donor mesenchymal stem cell-derived neuron-like cells into host neural network after rat spinal cord transection. Biomaterials. 10.1016/j.biomaterials.2015.02.073
Yanxian Feng et al. (2017) A macrophage-activating, injectable hydrogel to sequester endogenous growth factors for in situ angiogenesis. Biomaterials. 10.1016/j.biomaterials.2017.04.042
Yan Li et al. (2024) Chondroitin sulfate-modified antiangiogenic peptide conjugate induces cell apoptosis via the mitochondria-mediated pathway to perform antitumor activity. International Journal of Biological Macromolecules. 10.1016/j.ijbiomac.2024.129671
Xiaohui Wang et al. (2021) An oxidation responsive nano-radiosensitizer increases radiotherapy efficacy by remolding tumor vasculature. Biomaterials Science. 10.1039/D1BM00834J
Lu Zhang et al. (2025) Inhibition of Ovarian Cancer Growth, Metastasis and Reverse the Tumor Microenvironment by Dual Drug-Loaded Polymer Micelle Targeting Tumor Microenvironment. International Journal of Nanomedicine. 10.2147/IJN.S507038
Xiaohui Wang et al. (2021) Construction of an AuHQ nano-sensitizer for enhanced radiotherapy efficacy through remolding tumor vasculature. Journal of Materials Chemistry B. 10.1039/D1TB00515D
Zhang Runfang et al. (2021) Curcumin Derivative Cur20 Attenuated Cerebral Ischemic Injury by Antioxidant Effect and HIF-1α/VEGF/TFEB-Activated Angiogenesis. Frontiers in Pharmacology. 10.3389/fphar.2021.648107
Xin Tong et al. (2010) Decreased TIP30 Expression Promotes Tumor Metastasis in Lung Cancer. American Journal of Pathology. 10.2353/ajpath.2009.080846
Wajiha Ahmed et al. (2024) Multifunctional Drug- and AuNRs-Loaded ROS-Responsive Selenium-Containing Polyurethane Nanofibers for Smart Wound Healing. ACS Biomaterials Science & Engineering. 10.1021/acsbiomaterials.4c00363
