| Field | Specification |
|---|---|
| Target | |
| Alternative names | Versican core protein; Chondroitin sulfate proteoglycan core protein 2; Chondroitin sulfate proteoglycan 2; Glial hyaluronate-binding protein; GHAP; Large fibroblast proteoglycan; PG-M; VCAN; CSPG2 |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human Versican |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 18V68 is a rabbit monoclonal antibody that recognizes versican core protein (gene VCAN) in human, mouse and rat samples and is validated for Western blot and IHC. The predicted molecular weight is 372.8 kDa, and the supplier reports an observed band at about 373 kDa.
Versican is a large chondroitin sulfate proteoglycan of the extracellular matrix. It binds hyaluronan and helps organize the matrix around cells, influencing cell adhesion, migration and proliferation. Versican is studied in development, vascular biology, inflammation and tumor microenvironment research.
| Target | Versican core protein (gene VCAN; UniProt P13611, human) |
|---|---|
| Clone | 18V68 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 372.8 kDa |
| Observed MW | 373 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
Samples with a confirmed band (WB): mouse heart cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human versican.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt describes versican core protein as a secreted protein. Tissue expression noted by UniProt (human): Detected in placenta (at protein level). The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Yiming Li et al. (2018) Comparison of phenotypes and transcriptomes of mouse skin-derived precursors and dermal mesenchymal stem cells. Differentiation. 10.1016/j.diff.2018.07.001
Gongyan Liu et al. (2020) Isolation, culture and growth characteristics of dermal papilla cells from Rex rabbits. Tissue & Cell. 10.1016/j.tice.2020.101348
