| Field | Specification |
|---|---|
| Target | |
| Alternative names | Protein Wnt-2;Int-1-like protein 1;Int-1-related protein;IRP;WNT2;INT1L1, IRP; |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human WNT2 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone CAG-23 is a rabbit monoclonal antibody that recognizes protein Wnt-2 (gene WNT2) in human, mouse and rat samples and is validated for Western blot. The predicted molecular weight is 40.4 kDa, and the supplier reports an observed band at about 34 kDa.
Wnt-2 is a secreted Wnt ligand that signals through Frizzled receptors to activate the canonical β-catenin/TCF pathway. It acts upstream of FGF10 during embryonic lung development and has been implicated in the growth of midbrain dopaminergic precursors, so it is studied in organogenesis and tissue repair.
| Target | Protein Wnt-2 (gene WNT2; UniProt P09544, human) |
|---|---|
| Clone | CAG-23 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 40.4 kDa |
| Observed MW | 34 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Samples with a confirmed band (WB): Jurkat cells, SKBR-3 cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human WNT2.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt describes protein Wnt-2 as a secreted protein. Tissue expression noted by UniProt (human): Expressed in brain in the thalamus, in fetal and adult lung and in placenta. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
