| Field | Specification |
|---|---|
| Target | |
| Alternative names | Transcription factor atoh7; Atonal bHLH transcription factor 7; Helix-loop-helix protein zATH-5; zATH5; Protein atonal homolog 5; Protein atonal homolog 7; Protein lakritz; atoh7; ath5; lak |
| Gene ID | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived zebrafish ATOH7 recombinant protein (Position: M1-L134) |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody recognizes transcription factor atoh7 in zebrafish samples and is validated for IHC.
In zebrafish, atoh7 (also called lakritz) is a bHLH transcription factor required for the formation of retinal ganglion cells, the neurons that form the optic nerve. Zebrafish atoh7 mutants lack these cells, making it a key model for studying retinal neurogenesis.
| Target | Transcription factor atoh7 (gene atoh7; UniProt Q8AW52, zebrafish) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Zebrafish |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| IHC (paraffin sections) | 2–5 µg/mL (Zebrafish) |
|---|
Samples with confirmed staining (IHC): zebrafish eye tissue.
Recommended antigen retrieval: heat-mediated, in TE buffer (pH 9.0); citrate buffer (pH 6.0) can be used instead.
Immunogen
Recombinant zebrafish ATOH7 fragment (Met1–Leu134), expressed in E. coli.
Reactivity Notes
The supplier lists reactivity with zebrafish. UniProt places transcription factor atoh7 in the nucleus, perikaryon and cell projection.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
