| Field | Specification |
|---|---|
| Mfr No | |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Conjugate | |
| Form | Liquid |
| Host | |
| Isotype | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
Boster Bio Anti-Grik1b Antibody catalog # DZ33993. This antibody reacts with zebrafish. Key identifiers include target: grik1b, host: Rabbit, clonality: Polyclonal, isotype: Rabbit IgG, reactivity: Zebrafish, conjugate formats: Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, Fluoro647, Carrier Free.
Key elements and design rationale
- Purification: Immunogen affinity purified.
- Concentration: 500 μg/ml
- Format: Liquid
- Cellular localization (reported): Secreted.
- Tissue details (reported): Predominantly expressed in adult forebrain. Expressed in fetal brain, lung and kidney.
Biological background
Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity). SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.
Research relevance and current trends
- Axon guidance and circuit assembly in development and regeneration.
- Cell migration cues and receptor–ligand signaling in neural tissues.
- Spatial mapping of expression/localization across brain regions and model organisms.
Common research applications
- Western blot: Measure relative expression or size shifts across conditions in lysates.
- Immunofluorescence/ICC: Visualize subcellular localization and colocalization in cells.
- IHC: Assess tissue distribution and cell-type patterns in fixed sections.
Notes for experimental interpretation
- Use appropriate controls (secondary-only, isotype where relevant, and genetic or orthogonal controls when available) to support interpretation.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
