| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C34H47F3N2O2S2 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Anticancer agent 104 has been reported to possess anticancer activity, inducing apoptosis in cancer cells[1]. It is characterized by the molecular formula C34H47F3N2O2S2 and a molecular weight of 636.87 g/mol.
Physical & Chemical Properties
| CAS Number | 3047612-51-8 |
|---|---|
| Molecular Formula | C34H47F3N2O2S2 |
| Molecular Weight | 636.87 g/mol |
| SMILES | C[C@@]1(C(C)([C@@](CC1)([H])C2)C)[C@@H]2OC(CCC[C@@H]3[C@]4([H])[C@]5([H])[C@](CCCN5CCC4)([H])CN3C(SCC6=CC=C(C=C6)C(F)(F)F)=S)=O |
| Signaling Pathway | Apoptosis |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
In Vitro
In HepG2 cells, Anticancer agent 104 (48 h) is toxic, with IC50: 31.39 μM[1]. Anticancer agent 104 (10-200 μg/mL, 48 h) causes volume reduction and chromatin margination, and eventually apoptotic vesicles form[1]. Anticancer agent 104 (10-100 μg/mL, 48 h) triggers apoptosis in HepG2 cells[1].
Western Blot Analysis[1]
| Cell Line | Calu-1, SK-BR-3, HUH-7, 786-O, SK-OV-3 cells |
|---|---|
| Concentration | 0-200 μM approximately |
| Incubation Time | 48 h |
| Result | Shows cytotoxic activities with IC50s of 78.34, 44.18, 75.18, 91.67, 112.19 μM. |
Apoptosis Analysis[1]
| Cell Line | HepG2 cells |
|---|---|
| Concentration | 10, 50 and 100 μg/mL |
| Incubation Time | 48 h |
| Result | Showed apoptotic rate of 23.67%, 41.21% and 61.16% respectively. |
Data provided by the manufacturer. Numbered citations refer to the Literature Cited list in the product description.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).
