Anticancer agent 133

SKU:BHB21901404
Overview
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Anticancer agent 133 (CAS 2758905-51-8) is an inhibitor. Relevant to Apoptosis and Autophagy research. Molecular formula C24H19Cl3N5ORh, molecular weight 602.71 g/mol.
CAS Number 2758905-51-8
Molecular Weight 602.71 g/mol
Storage See Certificate of Analysis
Options selector
Catalog no. Size
HY-149344-50MG 50 mg
HY-149344-100MG 100 mg
HY-149344-250MG 250 mg
Available Options

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  • Options: Size: 50 mg, 100 mg, 250 mg
  • Lead time: confirmed on inquiry for every option.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
CAS no. 2758905-51-8
Applications
  • Functional Assay (In Vitro)
Molecular weight 602.71
Molecular formula C24H19Cl3N5ORh
SMILES Cl[Rh]12(Cl)([N]#CC)[N]3=C(C(N2C4=CC=CC=C4)=O)C(Cl)=CC=C3N5C(C6=CC=CC=C6)=CC(C)=[N]51
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-149344
Main SKU BHB21901404
Inhibitors

Compound Overview

Anticancer agent 133 is an anticancer compound with cytotoxic and antimetastatic activity that induces cell cycle arrest, apoptosis, and autophagy. It also suppresses cell metastasis by reducing EGFR expression through FAK-regulated integrin β1[1]. It has the molecular formula C24H19Cl3N5ORh and a molecular weight of 602.71 g/mol.

Physical & Chemical Properties

CAS Number 2758905-51-8
Molecular Formula C24H19Cl3N5ORh
Molecular Weight 602.71 g/mol
SMILES Cl[Rh]12(Cl)([N]#CC)[N]3=C(C(N2C4=CC=CC=C4)=O)C(Cl)=CC=C3N5C(C6=CC=CC=C6)=CC(C)=[N]51
Signaling Pathway Apoptosis; Autophagy; Protein Tyrosine Kinase/RTK; JAK/STAT Signaling
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Gu YQ, et al. Rhodium(III)-Picolinamide Complexes Act as Anticancer and Antimetastasis Agents via Inducing Apoptosis and Autophagy. J Med Chem. 2023 Jul 27;66(14):9592-9606.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.Why is there no price listed?
A.Every size of this product is quoted on inquiry. Send us the size you need and we will come back with price and lead time.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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