| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C27H27N9OS2 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Anticancer agent 158 is a potent anticancer agent, with IC50 values of 7.93 μM, 9.28 μM, 13.28 μM, and 181.89 μM reported for inhibition of HepG-2, MDA-MB-231, and HCT-116 cell lines[1]. It has a molecular formula of C27H27N9OS2 and a molecular weight of 557.69 g/mol.
Physical & Chemical Properties
| CAS Number | 2978685-72-0 |
|---|---|
| Molecular Formula | C27H27N9OS2 |
| Molecular Weight | 557.69 g/mol |
| SMILES | CC1=C(/C(C)=N/NC2=NC(C)=C(/N=N/C3=CC=C(OC)C=C3)S2)SC(N/N=C(C4=CNC5=C4C=CC=C5)\C)=N1 |
| Signaling Pathway | JAK/STAT Signaling; Protein Tyrosine Kinase/RTK |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
[1]. Al-Humaidi J Y, et al. Synthesis, Biological Evaluation, and Molecular Docking of Novel Azolylhydrazonothiazoles as Potential Anticancer Agents[J]. ACS Omega, 2023....
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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