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Scientific Background
CD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscles, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.
Product Overview
This monoclonal antibody (clone HIT2), raised in Mouse, recognizes CD38. It is validated for Flow Cytometry.
Validated Applications
| Applications | Flow Cytometry |
|---|
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
See specifications table.
Specifications
| Host | Mouse |
|---|---|
| Clonality | Monoclonal |
| Clone | HIT2 |
| Isotype | Mouse IgG1, κ |
| Conjugate | APC |
| Species Reactivity | Human |
| Concentration | 5 μL/Test |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| UniProt # | P28907 |
| Gene ID | 952 |
| Control Catalog Number | E-AB-F09792E |
| Lead Time | 2-3 business days |
| Validity | 12 months |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice packs |
| Target Synonyms | 2'-phospho-ADP-ribosyl cyclase;2'-phospho-cyclic-ADP-ribose transferase;ADP-ribosyl cyclase 1;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1;ADPRC 1;CD38;Cyclic ADP-ribose hydrolase 1;T10;cADPr hydrolase 1 |
Reactivity Notes
Validated reactivity: Human. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
Related Products
Explore related antibodies and reagents for CD38 research from Elabscience Biotechnology Co Ltd, or contact us for alternative formats.
Customization & Add-ons: Can't find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
